L.Q.C. Lamar (1825-1893), a lawyer, politician, and Civil War figure, lived in the house from 1868 until 1888. During the Civil War, Lamar organized the 19th Mississippi regiment of volunteers. He directed the law school at the University of Mississippi until he was elected to Congress in 1872, the first Democrat to represent Mississippi since Reconstruction. In 1877 Lamar was elected to the United States Senate and served until his appointment to President Grover Cleveland's Cabinet in 1884. Cleveland appointed Lamar to the United States Supreme Court in 1888 where he served until his death. Lamar is the only Mississippian to serve on the United States Supreme Court. He is the one of a very few to serve in all three branches of government. Lamar is buried in St. Peter's Cemetery in Oxford, Mississippi.
Located near Oxford's historic Courthouse Square, the L.Q.C. Lamar House was designated a National Historic Landmark in 1975. At that time the house was in poor condition. Seeing a unique opportunity to capture am important time in Mississippi's and the South's history , the Oxford-Lafayette County Heritage Foundation set about to repair, preserve, and restore the house and to turn it into a museum and community facility.
With the assistance of grants from "Save America's Treasures" program of the National Park Service and the Mississippi Department of Archives and History, the 1.3 million dollar project began in 2007. The project scope included the complete renovation of the interior and exterior as well as restoration of windows, woodwork and portions of the unique interior finishes. Alsoincluded was general structural repair.